Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18198891 | 1.00 | FGFR1 (0.38) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL30236077 | 0.87 | CYP4F2 (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL30388040 | 0.87 | CYP4F2 (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29387740 | 0.87 | RET (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4053570 | 0.87 | RET (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL32682437 | 0.87 | RET (0.33) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4905166 | 0.87 | CYP4F2 (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28684897 | 0.87 | RET (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL30792270 | 0.87 | RET (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28684894 | 0.87 | RET (0.37) | FGFR1KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928964-B | Synthetic method of axitinib intermediate | 江苏开元药业有限公司 | 2022-04-15 | — | — | CN | disclosed |