Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 20/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.66 |
| ▸ | ATR | Q13535 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18631938 | 1.00 | ATM (0.73) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL18631954 | 0.86 | ATM (0.70) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL30189167 | 0.84 | ATM (0.54) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL21911421 | 0.84 | ATM (0.54) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL18631962 | 0.83 | ATM (0.55) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL18631960 | 0.82 | ATM (1.00) | ATMPIK3CAKCNH2 | |
| SCHEMBL18843803 | 0.81 | ATM (1.00) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL22640346 | 0.81 | ATM (0.88) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL18631990 | 0.81 | ATM (0.98) | ATMPIK3CAKCNH2ATR | |
| SCHEMBL18651657 | 0.81 | ATM (0.77) | ATMPIK3CAKCNH2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431139-B | Deuterated imidazo [4,5-c ] quinolin-2-one compounds and their use in treating cancer | 阿斯利康(瑞典)有限公司 | 2022-07-05 | — | — | CN | disclosed |