Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17241561 | 1.00 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL17246311 | 0.94 | DHODH (0.55) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL14341439 | 0.88 | DHODH (0.67) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10861648 | 0.88 | DHODH (0.67) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL23953819 | 0.86 | DHODH (0.45) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL13930268 | 0.85 | DHODH (0.63) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL25357063 | 0.85 | DHODH (0.58) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11389721 | 0.84 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL18987933 | 0.84 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL31080679 | 0.84 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431139-B | Deuterated imidazo [4,5-c ] quinolin-2-one compounds and their use in treating cancer | 阿斯利康(瑞典)有限公司 | 2022-07-05 | — | — | CN | disclosed |