Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 18/20 | 0.50 |
| ▸ | ITK | Q08881 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435736 | 1.00 | GRM4 (0.50) | GRM4ITKCYP1A2 | |
| SCHEMBL14895764 | 0.82 | TDP1 (0.42) | GRM4ITKCYP1A2 | |
| SCHEMBL29603514 | 0.82 | GRM4 (0.42) | GRM4ITKCYP1A2 | |
| SCHEMBL4061359 | 0.81 | GRM4 (0.48) | GRM4ITK | |
| SCHEMBL27143770 | 0.81 | GRM4 (0.51) | GRM4ITKCYP1A2 | |
| Hydrochloric Acid SCHEMBL31277116 | 0.80 | GRM4 (0.45) | GRM4ITK | |
| SCHEMBL30036160 | 0.80 | GRM4 (0.45) | GRM4ITK | |
| SCHEMBL29604083 | 0.79 | GRM4 (0.40) | GRM4ITKCYP1A2 | |
| SCHEMBL27332981 | 0.77 | GRM4 (0.43) | GRM4ITK | |
| SCHEMBL30036112 | 0.76 | TSHR (0.54) | GRM4ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |