Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SOD1 | P00441 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471132 | 1.00 | MAOB (0.55) | MAOBALDH1A1MAPTRAB9AGPR3 | |
| SCHEMBL10972329 | 0.86 | MAPT (0.59) | ALDH1A1MAPTGPR3HTTL3MBTL1 | |
| SCHEMBL16108829 | 0.85 | MAOB (0.51) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL27075523 | 0.85 | MAOB (0.51) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL23363616 | 0.82 | MAOB (0.49) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL14241249 | 0.82 | MAOB (0.49) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL29899125 | 0.82 | MAOB (0.49) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL14227129 | 0.82 | MAOB (0.49) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL2795588 | 0.81 | MAOB (0.54) | MAOBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL3636719 | 0.81 | MAOB (0.55) | MAOBALDH1A1MAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |