Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.59 |
| ▸ | REN | P00797 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310095 | 0.99 | CTSC (0.58) | CTSCRENMMEEEDLMNA | |
| SCHEMBL30553112 | 0.96 | CTSC (0.59) | CTSCRENMMELMNATDP1 | |
| SCHEMBL29702042 | 0.94 | CTSC (0.63) | CTSCRENMMELMNATDP1 | |
| SCHEMBL30546877 | 0.94 | CTSC (0.63) | CTSCRENMMELMNATDP1 | |
| SCHEMBL29701979 | 0.94 | CTSC (0.63) | CTSCRENMMELMNATDP1 | |
| SCHEMBL30567412 | 0.91 | CTSC (0.49) | CTSCRENKLK7 | |
| SCHEMBL29630752 | 0.90 | CTSC (0.48) | CTSCRENKLK7 | |
| SCHEMBL30517397 | 0.90 | CTSC (0.58) | CTSCRENMMEEEDLMNA | |
| SCHEMBL14903320 | 0.90 | CTSC (0.52) | CTSCRENMMEEEDGHSR | |
| SCHEMBL14903448 | 0.90 | CTSC (0.52) | CTSCRENMMEEEDGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284255-A | Targeting polypeptide compound for early colorectal tumor and application | 中国医学科学院药物研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-110041400-B | Polypeptide and application thereof in early diagnosis of colorectal cancer | 中国医学科学院药物研究所 | 2022-07-29 | — | — | CN | disclosed |