Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043959 | 1.00 | CRBN (0.56) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL23051651 | 0.87 | CRBN (0.50) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL23051560 | 0.86 | CRBN (0.53) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL24031698 | 0.86 | AR (0.53) | CRBNARDDB1ALDH1A1TSHR | |
| SCHEMBL26818516 | 0.83 | AR (0.54) | CRBNARDDB1ALDH1A1TSHR | |
| SCHEMBL26802808 | 0.83 | CRBN (0.52) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL26929043 | 0.82 | CRBN (0.62) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL30692984 | 0.82 | CRBN (0.62) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL30043230 | 0.80 | CRBN (0.71) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL30312919 | 0.80 | CRBN (0.71) | CRBNARDDB1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021580-A1 | CEREBLON E3 LIGASE INHIBITORS | The Regents Of The University Of Michigan (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-114641337-A | CEREBLON E3 ligase inhibitors | 密歇根大学董事会 | 2022-06-17 | — | — | CN | disclosed |