⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614810 | 0.93 | BLM (0.54) | — | |
| SCHEMBL7624518 | 0.91 | ACE2 (0.53) | — | |
| SCHEMBL21603084 | 0.91 | ACE2 (0.53) | — | |
| SCHEMBL4849724 | 0.91 | ACE2 (0.53) | — | |
| SCHEMBL22043021 | 0.91 | ACE2 (0.53) | — | |
| SCHEMBL297723 | 0.84 | — | — | |
| SCHEMBL233225 | 0.84 | BLM (0.73) | — | |
| SCHEMBL17285499 | 0.84 | BLM (0.73) | — | |
| SCHEMBL7179523 | 0.84 | BLM (0.65) | — | |
| SCHEMBL16330413 | 0.84 | BLM (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450742-B1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-07-06 | — | — | EP | claimed |
| EP-0047451-B1 | FLUORO AND CHLOROMETHYLTHIOAMINO-BENZAMIDES, PREPARATION AND USE THEREOF | BAYER AG (DE) | 1984-02-01 | — | — | EP | claimed |
| US-20240118270-A1 | METHOD FOR STABILIZING EXTRACELLULAR VESICLES | H.U. GROUP RESEARCH INSTITUTE G.K. (JP) | 2024-04-11 | — | — | US | disclosed |
| US-20230227916-A1 | METHOD FOR RECOVERING EXTRACELLULAR VESICLE | H.U. GROUP RESEARCH INSTITUTE G.K. (JP) | 2023-07-20 | — | — | US | disclosed |
| EP-4137559-A1 | METHOD FOR HARVESTING EXTRACELLULAR VESICLES | H.U. Group Research Institute G.K. (JP) | 2023-02-22 | — | — | EP | disclosed |
| CN-115461445-A | Method for recovering extracellular vesicles | 合同会社予幸集团中央研究所 | 2022-12-09 | — | — | CN | disclosed |
| US-20210396633-A1 | METHOD FOR RECOVERING EXTRACELLULAR VESICLES | H.U. GROUP RESEARCH INSTITUTE G.K. (JP) | 2021-12-23 | — | — | US | disclosed |
| CN-113039422-A | Method for recovering extracellular vesicles | 合同会社予幸集团中央研究所 | 2021-06-25 | — | — | CN | disclosed |
| EP-3730603-A1 | METHOD FOR STABILIZING EXTRACELLULAR VESICLES | H.U. Group Research Institute G.K. (JP) | 2020-10-28 | — | — | EP | disclosed |
| US-20200319175-A1 | METHOD FOR STABILIZING EXTRACELLULAR VESICLES | MIRACA RESEARCH INSTITUTE G.K. (JP) | 2020-10-08 | — | — | US | disclosed |
| US-10759749-B2 | Therapeutic agent for diabetes | JCR PHARMACEUTICALS CO., LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994000124-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | WEBER ECKARD (US) | 1994-01-06 | — | — | WO | disclosed |
| US-5194432-A | Drugs for treatment of infectious diseases; microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-16 | — | — | US | disclosed |
| US-4960766-A | SUBSTITUTED 2-PYRAZOLIOMETHYL GROUP AND A 7-(AMINOTHIAZOLYL) (ALKOXYIMINO)-ACETAMIDO GROUP CEPHALOSPORIN DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4906662-A | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0263229-A1 | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-04-13 | — | — | EP | disclosed |
| EP-0223246-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |
| CN-86107947-A | New cephem compounds and preparation method thereof | — | 1987-05-27 | — | — | CN | disclosed |
| US-4188403-A | Cyclopentan-1-amines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-02-12 | — | — | US | disclosed |