Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.69 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16338004 | 1.00 | BTK (0.69) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL29709442 | 0.82 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL16336659 | 0.82 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL16336006 | 0.81 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL29709483 | 0.81 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL23518677 | 0.81 | BTK (0.44) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL16337009 | 0.81 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL29709509 | 0.81 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL16336471 | 0.80 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 | |
| SCHEMBL16337884 | 0.79 | BTK (1.00) | BTKPLK4CHEK1DAPK3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008328-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | AbbVie Inc. (US) | 2022-06-08 | — | — | EP | disclosed |