Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24792946 | 1.00 | ABCB1 (0.44) | ABCB1POLBMYCMAXCYP11B1 | |
| SCHEMBL29079980 | 0.77 | PDK4 (0.43) | KDM4E | |
| SCHEMBL30082696 | 0.76 | MAPT (0.43) | ABCB1POLBMYCMAXALDH1A1 | |
| SCHEMBL24794238 | 0.76 | MAPT (0.43) | ABCB1POLBMYCMAXALDH1A1 | |
| SCHEMBL4718694 | 0.75 | MAPT (0.56) | ALDH1A1KDM4EMAPTTLR9TLR7 | |
| SCHEMBL22120856 | 0.72 | MEN1 (0.41) | ABCB1POLBMYCMAXALDH1A1 | |
| SCHEMBL22154655 | 0.72 | MEN1 (0.41) | ABCB1POLBMYCMAXALDH1A1 | |
| SCHEMBL24794000 | 0.72 | POLB (0.38) | ABCB1POLBMYCMAXALDH1A1 | |
| SCHEMBL6592921 | 0.72 | MYC (0.48) | ABCB1POLBMYCMAXCYP11B1 | |
| SCHEMBL6592912 | 0.72 | MYC (0.48) | ABCB1POLBMYCMAXCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761386-A | Substituted N-heterocyclic carboxamides as acid ceramidase inhibitors and their use as pharmaceuticals | 比亚尔R&D投资股份公司 | 2022-07-15 | — | — | CN | disclosed |