Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712048 | 0.90 | RXFP1 (0.53) | RXFP1KMT2APOLBMEN1TDP1 | |
| SCHEMBL29712010 | 0.90 | RXFP1 (0.53) | RXFP1KMT2APOLBMEN1TDP1 | |
| SCHEMBL29640468 | 0.90 | RXFP1 (0.53) | RXFP1KMT2APOLBMEN1TDP1 | |
| SCHEMBL30104709 | 0.90 | RXFP1 (0.53) | RXFP1KMT2APOLBMEN1TDP1 | |
| SCHEMBL29640463 | 0.86 | RXFP1 (0.52) | RXFP1KMT2APOLBTDP1 | |
| SCHEMBL29640492 | 0.86 | RXFP1 (0.52) | RXFP1KMT2APOLBTDP1 | |
| SCHEMBL29711976 | 0.86 | RXFP1 (0.59) | RXFP1KMT2APOLBTDP1 | |
| SCHEMBL29640508 | 0.82 | RXFP1 (0.51) | RXFP1KMT2APOLBTDP1 | |
| SCHEMBL29640443 | 0.82 | RXFP1 (0.51) | RXFP1KMT2APOLBTDP1 | |
| SCHEMBL29640436 | 0.81 | RXFP1 (0.62) | RXFP1KMT2APOLBMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010341-A1 | TRKB POSITIVE ALLOSTERIC MODULATORS | Université de Strasbourg (FR) | 2022-06-15 | — | — | EP | disclosed |