Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 9/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.51 |
| ▸ | SYK | P43405 | 7/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19666661 | 1.00 | MAPK8 (0.51) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666660 | 1.00 | MAPK8 (0.51) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666532 | 0.98 | MAPK8 (0.51) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666534 | 0.98 | MAPK8 (0.51) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL29717686 | 0.98 | MAPK8 (0.51) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666606 | 0.96 | MAPK8 (0.55) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666605 | 0.96 | MAPK8 (0.55) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL29717699 | 0.96 | MAPK8 (0.55) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666279 | 0.92 | MAPK8 (0.49) | MAPK8MAPK9SYKPDGFRBPDGFRA | |
| SCHEMBL19666631 | 0.92 | MAPK8 (0.49) | MAPK8MAPK9SYKPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476696-B | Anti-trypanosome and anti-leishmania agents for animals and humans | 细胞基因公司 | 2022-06-10 | — | — | CN | disclosed |