Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 3/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 12/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20916536 | 1.00 | KCNJ6 (0.49) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL19552003 | 1.00 | KCNJ6 (0.49) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL19552097 | 0.87 | P2RX4 (0.50) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL19552096 | 0.87 | P2RX4 (0.50) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL29718829 | 0.87 | P2RX4 (0.50) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL19552137 | 0.87 | KCNJ6 (0.53) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL19552139 | 0.87 | KCNJ6 (0.53) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL29718782 | 0.87 | KCNJ5 (0.48) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL20916579 | 0.87 | KCNJ5 (0.48) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA | |
| SCHEMBL19553414 | 0.87 | KCNJ5 (0.48) | KCNJ6KCNJ5KCNJ3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984003-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115054600-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115054600-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114984003-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-109415321-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-06-17 | — | — | CN | disclosed |