Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 14/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22976533 | 1.00 | SSTR2 (0.38) | SSTR2USP30SMPD3JAK3BTK | |
| SCHEMBL22976537 | 1.00 | SSTR2 (0.38) | SSTR2USP30SMPD3JAK3BTK | |
| SCHEMBL29653485 | 0.87 | JAK3 (0.50) | JAK3BTK | |
| SCHEMBL22976842 | 0.87 | SMPD3 (0.35) | SSTR2SMPD3BTK | |
| SCHEMBL22976844 | 0.87 | SMPD3 (0.35) | SSTR2SMPD3BTK | |
| SCHEMBL31243202 | 0.82 | SSTR2 (0.39) | SSTR2CYP2C9CYP2C19SSTR4CYP3A4 | |
| SCHEMBL28777639 | 0.82 | SSTR2 (0.39) | SSTR2CYP2C9CYP2C19SSTR4CYP3A4 | |
| SCHEMBL28777644 | 0.82 | SSTR2 (0.39) | SSTR2CYP2C9CYP2C19SSTR4CYP3A4 | |
| SCHEMBL22976403 | 0.80 | JAK2 (0.35) | SSTR2USP30JAK3BTK | |
| SCHEMBL22976400 | 0.80 | JAK2 (0.35) | SSTR2USP30JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294797-A1 | CRYSTALLINE FORMS OF A SOMATOSTATIN MODULATOR | Crinetics Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022177974-A1 | CRYSTALLINE FORMS OF A SOMATOSTATIN MODULATOR | Crinetics Pharmaceuticals, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |
| EP-4013748-A1 | NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |