Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22976570 | 1.00 | BTK (0.50) | BTKJAK3CTSKCKS1BSKP1 | |
| SCHEMBL22976566 | 1.00 | BTK (0.50) | BTKJAK3CTSKCKS1BSKP1 | |
| SCHEMBL29653485 | 0.89 | JAK3 (0.50) | BTKJAK3CTSKCKS1BSKP1 | |
| SCHEMBL29653479 | 0.88 | JAK3 (0.45) | BTKJAK3CTSKCKS1BSKP1 | |
| SCHEMBL26353326 | 0.88 | JAK3 (0.45) | BTKJAK3CTSKCKS1BSKP1 | |
| SCHEMBL22976593 | 0.87 | SUV39H2 (0.43) | BTKJAK3CKS1BSKP1SKP2 | |
| SCHEMBL22976596 | 0.87 | SUV39H2 (0.43) | BTKJAK3CKS1BSKP1SKP2 | |
| SCHEMBL29719951 | 0.87 | SUV39H2 (0.43) | BTKJAK3CKS1BSKP1SKP2 | |
| SCHEMBL22976526 | 0.80 | RET (0.42) | BTKJAK3RET | |
| SCHEMBL22976524 | 0.80 | RET (0.42) | BTKJAK3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504705-A | Non-peptide somatostatin 5 receptor agonists and uses thereof | 克林提克斯医药股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114585614-B | Non-peptide somatostatin 5 receptor agonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-12-03 | — | — | CN | disclosed |
| EP-4294797-A1 | CRYSTALLINE FORMS OF A SOMATOSTATIN MODULATOR | Crinetics Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| CN-117043149-A | Crystalline forms of somatostatin modulators | 克林提克斯医药股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022177974-A1 | CRYSTALLINE FORMS OF A SOMATOSTATIN MODULATOR | Crinetics Pharmaceuticals, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |
| EP-4013748-A1 | NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |