SCHEMBL29720444 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	PTGER4	P35408	9/20	0.55

▸	PTGER2	P43116	1/20	0.51

▸	KDM4E	B2RXH2	1/20	0.40

▸	MAPT	P10636	1/20	0.40

▸	LMNA	P02545	1/20	0.35

▸	NPSR1	Q6W5P4	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	AKR1C3	P42330	1/20	0.33

▸	AKR1C2	P52895	1/20	0.33

▸	GPBAR1	Q8TDU6	3/20	0.33

▸	POLB	P06746	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26417055	1.00	PTGER4 (0.55)	PTGER4PTGER2KDM4EMAPTLMNA
SCHEMBL875993	0.85	PTGER4 (0.71)	PTGER4PTGER2KDM4EMAPTLMNA
SCHEMBL15239116	0.85	PTGER4 (0.69)	PTGER4PTGER2KDM4EMAPTLMNA
SCHEMBL876516	0.84	PTGER4 (0.69)	PTGER4PTGER2KDM4EMAPTLMNA
SCHEMBL24861855	0.83	PTGER4 (0.82)	PTGER4PTGER2
SCHEMBL26906388	0.83	PTGER4 (0.82)	PTGER4PTGER2
SCHEMBL26418788	0.83	PTGER4 (0.66)	PTGER4PTGER2KDM4EMAPTLMNA
SCHEMBL876698	0.82	PTGER4 (0.70)	PTGER4PTGER2KDM4EMAPTLMNA
SCHEMBL29720569	0.81	CYP1A2 (0.49)	PTGER4PTGER2LMNANPSR1SMN1; SMN2
SCHEMBL26417056	0.81	CYP1A2 (0.49)	PTGER4PTGER2LMNANPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022161418-A1	PYRAZOLAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF	深圳晶泰科技有限公司	2022-08-04	—	—	WO	disclosed