Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 13/20 | 0.73 |
| ▸ | TYRO3 | Q06418 | 9/20 | 0.67 |
| ▸ | AXL | P30530 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720912 | 0.93 | TYRO3 (0.68) | MERTKTYRO3AXL | |
| SCHEMBL29720695 | 0.86 | TYRO3 (0.71) | MERTKTYRO3AXL | |
| SCHEMBL19377873 | 0.84 | MERTK (0.78) | MERTKTYRO3AXL | |
| SCHEMBL29720855 | 0.84 | TYRO3 (0.71) | MERTKTYRO3AXL | |
| SCHEMBL19377793 | 0.84 | MERTK (1.00) | MERTKTYRO3AXL | |
| SCHEMBL29720858 | 0.84 | TYRO3 (0.68) | MERTKTYRO3AXL | |
| SCHEMBL29720718 | 0.84 | AXL (0.52) | MERTKTYRO3AXL | |
| SCHEMBL28341757 | 0.84 | AXL (0.52) | MERTKTYRO3AXL | |
| SCHEMBL19377688 | 0.83 | MERTK (0.85) | MERTKTYRO3AXL | |
| SCHEMBL30874313 | 0.83 | MERTK (0.85) | MERTKTYRO3AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627796-B | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |