Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.49 |
| ▸ | PDE4A | P27815 | 14/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972153 | 1.00 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL2971159 | 1.00 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL2980682 | 1.00 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL2980679 | 1.00 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL2980324 | 0.94 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL5704662 | 0.94 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL2966656 | 0.87 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL5704555 | 0.87 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL5704516 | 0.82 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2978829 | 0.82 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772258-B2 | Agent for treatment of allergic eye disease | NIKKEN CHEMICALS CO., LTD. (JP) | 2010-08-10 | — | — | US | claimed |
| US-20080306163-A1 | AGENT FOR TREATMENT OF ALLERGIC EYE DISEASE | NIKKEN CHEMICALS CO., LTD. | 2008-12-11 | — | — | US | claimed |
| EP-1410795-A1 | REMEDIES FOR ALLERGIC EYE DISEASES | Nikken Chemicals Company, Limited (JP) | 2004-04-21 | — | — | EP | claimed |
| US-7772258-B2 | Agent for treatment of allergic eye disease | NIKKEN CHEMICALS CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1410795-B1 | REMEDIES FOR ALLERGIC EYE DISEASES | NIKKEN CHEMICALS CO LTD (JP) | 2009-10-14 | — | — | EP | disclosed |
| US-20080306163-A1 | AGENT FOR TREATMENT OF ALLERGIC EYE DISEASE | NIKKEN CHEMICALS CO., LTD. | 2008-12-11 | — | — | US | disclosed |
| US-6943195-B2 | Cycloalkenone derivative | NIKKEN CHEMICALS CO., LTD (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20040157933-A1 | Cycloalkenone derivative | NIKKEN CHEMICALS CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1410795-A1 | REMEDIES FOR ALLERGIC EYE DISEASES | Nikken Chemicals Company, Limited (JP) | 2004-04-21 | — | — | EP | disclosed |
| EP-1405844-A1 | CYCLOALKENONE DERIVATIVE | Nikken Chemicals Company, Limited (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306163-A1 | AGENT FOR TREATMENT OF ALLERGIC EYE DISEASE | HRH4, HRH3, HRH2 | PDE4B 2422/4885PDE4A 2224/4885PDE4C 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.