Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148104 | 0.86 | KDM4E (0.53) | IDO1RHEBFLT3NPC1POLB | |
| SCHEMBL29540084 | 0.77 | IDO1 (0.54) | IDO1CLK1CDK5DYRK1ACDK5R1 | |
| SCHEMBL29394458 | 0.77 | FLT3 (0.66) | IDO1RHEBFLT3NPC1POLB | |
| SCHEMBL24447653 | 0.77 | FLT3 (0.66) | IDO1RHEBFLT3NPC1POLB | |
| SCHEMBL741480 | 0.76 | MAP2K1 (0.49) | CDK5DYRK1ARHEBFLT3CCNC | |
| SCHEMBL8115640 | 0.76 | MAP2K1 (0.37) | RHEBCCNCCDK8MKNK1MKNK2 | |
| SCHEMBL29063057 | 0.76 | RHEB (0.65) | IDO1RHEBFLT3KDM4EHPGD | |
| SCHEMBL20504845 | 0.76 | RHEB (0.45) | IDO1RHEBFLT3POLBKDM4E | |
| SCHEMBL4785003 | 0.73 | KMT2A (0.54) | IDO1RHEBSYKFLT3POLB | |
| SCHEMBL24843801 | 0.72 | CHUK (0.35) | IDO1CLK1CDK5DYRK1ACDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |