Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 10/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180128 | 0.89 | HCRTR2 (0.48) | HCRTR2RAF1BRAFGRIN2BPDE4D | |
| SCHEMBL27180131 | 0.89 | HCRTR2 (0.48) | HCRTR2RAF1BRAFGRIN2BPDE4D | |
| SCHEMBL24529350 | 0.83 | TLR9 (0.37) | HCRTR2TLR9TLR8TLR7PDE4D | |
| SCHEMBL27179588 | 0.82 | HCRTR2 (0.60) | HCRTR2TLR9TLR8TLR7RAF1 | |
| SCHEMBL29723610 | 0.82 | HCRTR2 (0.60) | HCRTR2TLR9TLR8TLR7RAF1 | |
| SCHEMBL24529371 | 0.82 | HCRTR2 (0.60) | HCRTR2TLR9TLR8TLR7RAF1 | |
| SCHEMBL27179589 | 0.82 | HCRTR2 (0.60) | HCRTR2TLR9TLR8TLR7RAF1 | |
| SCHEMBL24387029 | 0.80 | HCRTR2 (0.54) | HCRTR2 | |
| SCHEMBL24529325 | 0.77 | HCRTR2 (0.54) | HCRTR2HDAC6 | |
| SCHEMBL27179410 | 0.77 | HCRTR2 (0.54) | HCRTR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4262788-B1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2026-01-21 | — | — | EP | disclosed |