Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729846 | 0.89 | MAP4K1 (0.48) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29729851 | 0.88 | SRC (0.54) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29729786 | 0.87 | MAP4K1 (0.47) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29730017 | 0.86 | ALK (0.52) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29730005 | 0.85 | ALK (0.61) | EGFRALKJAK2SRCTYK2 | |
| Hydrochloric Acid SCHEMBL29730045 | 0.84 | BRD4 (0.50) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29729870 | 0.83 | EGFR (0.45) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29729815 | 0.83 | CDK4 (0.50) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29730001 | 0.83 | SLC2A1 (0.50) | EGFRALKJAK3JAK2ERBB2 | |
| SCHEMBL29729898 | 0.79 | MKNK1 (0.55) | EGFRALKJAK3JAK2ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131741-A1 | ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2022-06-23 | — | — | WO | disclosed |