⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21737377 | 0.76 | — | — | |
| SCHEMBL15109619 | 0.74 | — | — | |
| SCHEMBL8044610 | 0.74 | — | — | |
| SCHEMBL30798549 | 0.73 | — | — | |
| SCHEMBL17188850 | 0.73 | — | — | |
| SCHEMBL6261221 | 0.70 | — | — | |
| SCHEMBL18768832 | 0.70 | — | — | |
| SCHEMBL20057541 | 0.70 | — | — | |
| SCHEMBL12536198 | 0.69 | — | — | |
| SCHEMBL15679985 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634491-B | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114634491-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2022-06-17 | — | — | CN | disclosed |