SCHEMBL29736133

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C

nearest known ligand 0.72

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	20/20	0.72

▸	BACE2	Q9Y5Z0	5/20	0.72

▸	CTSD	P07339	2/20	0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30502352	0.91	BACE1 (0.66)	BACE1BACE2CTSD
SCHEMBL29598002	0.91	BACE1 (0.68)	BACE1BACE2CTSD
SCHEMBL38659301	0.90	BACE1 (0.63)	BACE1BACE2CTSD
SCHEMBL31575679	0.89	BACE1 (0.67)	BACE1BACE2CTSD
SCHEMBL30974149	0.88	BACE1 (0.58)	BACE1BACE2CTSD
SCHEMBL30586759	0.88	BACE1 (0.60)	BACE1BACE2CTSD
SCHEMBL30262191	0.88	BACE1 (0.59)	BACE1BACE2CTSD
SCHEMBL31415952	0.88	NPY4R (0.58)	BACE1BACE2CTSD
SCHEMBL38658074	0.88	BACE1 (0.60)	BACE1BACE2CTSD
SCHEMBL30512850	0.88	BACE1 (0.67)	BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed