Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.52 |
| ▸ | JAK1 | P23458 | 14/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24498077 | 1.00 | TYK2 (0.52) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL29686980 | 0.94 | TYK2 (0.50) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL29686397 | 0.93 | TYK2 (0.46) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL24498054 | 0.93 | TYK2 (0.46) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL29686586 | 0.93 | TYK2 (0.47) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL24497662 | 0.93 | TYK2 (0.47) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL24497674 | 0.92 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL29686389 | 0.92 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL24498496 | 0.88 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL29686474 | 0.88 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186070-A | Hydroxamate compound and crystalline form of salt thereof and preparation method thereof | 深圳微芯生物科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |