Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 6/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686204 | 1.00 | METAP1 (0.39) | METAP1TYK2IDO1BRD9AAK1 | |
| SCHEMBL24498041 | 1.00 | METAP1 (0.39) | METAP1TYK2IDO1BRD9AAK1 | |
| SCHEMBL30695862 | 0.86 | TYK2 (0.50) | METAP1TYK2IDO1BRD9RXFP1 | |
| SCHEMBL26124861 | 0.85 | TYK2 (0.43) | TYK2ALOX5APFEN1 | |
| SCHEMBL29686569 | 0.83 | AAK1 (0.36) | TYK2AAK1PIK3CDABL1EGFR | |
| SCHEMBL24498474 | 0.81 | TYK2 (0.50) | METAP1TYK2IDO1BRD9 | |
| SCHEMBL29686078 | 0.81 | TYK2 (0.50) | METAP1TYK2IDO1BRD9 | |
| SCHEMBL28838921 | 0.81 | TYK2 (0.40) | METAP1TYK2IDO1BRD9RXFP1 | |
| SCHEMBL29686656 | 0.81 | TYK2 (0.40) | METAP1TYK2IDO1BRD9RXFP1 | |
| SCHEMBL30695861 | 0.77 | METAP1 (0.46) | METAP1TYK2BRD9RXFP1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |