Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573582 | 1.00 | CHRM2 (0.37) | CHRM2CHRM4CHRM5CHRM3TTR | |
| Hydrochloric Acid SCHEMBL25245581 | 0.97 | CHRM2 (0.36) | CHRM2CHRM4CHRM5CHRM3TTR | |
| SCHEMBL29023882 | 0.97 | — | — | |
| SCHEMBL28436926 | 0.97 | TTR (0.40) | CHRM2CHRM4CHRM5CHRM3TTR | |
| SCHEMBL16878490 | 0.94 | — | — | |
| SCHEMBL18885585 | 0.91 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7274558 | 0.89 | — | — | |
| SCHEMBL16878223 | 0.88 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7268795 | 0.84 | — | — | |
| SCHEMBL15824288 | 0.84 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019519-A1 | NOVEL DIHYDROPYRIMIDINOISOQUINOLINONES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | Galapagos N.V. (BE) | 2022-06-29 | — | — | EP | disclosed |