Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 14/20 | 0.40 |
| ▸ | PRKDC | P78527 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 10/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.36 |
| ▸ | ATR | Q13535 | 3/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23119289 | 0.90 | ATM (0.42) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29688033 | 0.90 | ATM (0.42) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29688251 | 0.88 | ATM (0.42) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL23119283 | 0.88 | ATM (0.42) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL21541840 | 0.87 | PRKDC (0.49) | CTSSCTSKATMPRKDCMTOR | |
| SCHEMBL23119299 | 0.86 | ATM (0.54) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL23093830 | 0.86 | ATM (0.54) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL23119298 | 0.86 | ATM (0.54) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL30192398 | 0.85 | PIK3CB (0.36) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23119186 | 0.82 | ATM (0.49) | ATMPRKDCMTORPIK3CAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787162-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-119215050-A | Application of substituted imidazoquinoxaline compound in preparation of anti-cancer drugs | 上海瑛派药业有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119080781-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-114787162-B | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114787162-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2022-07-22 | — | — | CN | disclosed |