Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31517351 | 0.93 | KDM4E (0.37) | PDE2AKDM4EHTTPDE3AKDM5A | |
| SCHEMBL6606933 | 0.84 | PDE2A (0.35) | PDE2APDE3BKMT2AKDM4EHTT | |
| SCHEMBL6604117 | 0.81 | PDE2A (0.34) | PDE2APDE3BKMT2AKDM4EHTT | |
| SCHEMBL6605266 | 0.76 | KDM4E (0.36) | PDE2AKMT2AKDM4EHTTTDP1 | |
| SCHEMBL19723894 | 0.69 | HCAR2 (0.42) | KDM4EHTTSMN1; SMN2HCAR2NR1I2 | |
| SCHEMBL19723890 | 0.68 | HCAR2 (0.41) | PDE2APDE3BKDM4EHTTHCAR2 | |
| SCHEMBL12539281 | 0.67 | PDE2A (0.46) | PDE2APDE3BPDE3AHCAR2 | |
| SCHEMBL14014971 | 0.66 | KDM4E (0.54) | PDE2APDE3BKMT2AKDM4EHTT | |
| SCHEMBL25635468 | 0.65 | HCAR2 (0.45) | PDE2APDE3BKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29042582 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212833-B | Phenylpyridine derivatives and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2022-09-06 | — | — | CN | disclosed |
| EP-3696176-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2022-05-04 | — | — | EP | disclosed |