Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613485 | 1.00 | HSD17B10 (0.47) | HSD17B10KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL29746003 | 0.85 | ESR1 (0.49) | HSD17B10KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL26613351 | 0.85 | ESR1 (0.49) | HSD17B10KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL14582276 | 0.82 | ESR1 (0.48) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL26613539 | 0.79 | JAK2 (0.43) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL29746559 | 0.79 | JAK2 (0.43) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14582275 | 0.79 | MEN1 (0.49) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL29746154 | 0.78 | ESR1 (0.49) | MAPTESR1ESR2MTNR1ANAPRT | |
| SCHEMBL26613571 | 0.78 | ESR1 (0.49) | MAPTESR1ESR2MTNR1ANAPRT | |
| SCHEMBL28470501 | 0.77 | ESR1 (0.50) | HSD17B10KDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403554-A | Therapeutic or prophylactic agent for amyotrophic lateral sclerosis | 东丽株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-116648245-A | Tetrahydroquinoline derivative and medical application thereof | 东丽株式会社 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022138888-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | 東レ株式会社 | 2022-06-30 | — | — | WO | disclosed |