⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31460294 | 0.80 | CYP1A2 (0.31) | — | |
| SCHEMBL29753717 | 0.74 | — | — | |
| SCHEMBL9566400 | 0.70 | — | — | |
| SCHEMBL16984316 | 0.70 | — | — | |
| SCHEMBL23466226 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL9566486 | 0.68 | — | — | |
| SCHEMBL24819506 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL30037141 | 0.65 | — | — | |
| SCHEMBL16984975 | 0.64 | TSHR (0.30) | — | |
| SCHEMBL11759566 | 0.64 | HTR2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12569564-B2 | Spirocyclic MDM2 modulator and uses thereof | NEWAVE PHARMACEUTICAL INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-20250073340-A1 | SPIROCYCLIC MDM2 MODULATOR AND USES THEREOF | NEWAVE PHARMACEUTICAL INC. | 2025-03-06 | — | — | US | disclosed |
| WO-2022159644-A1 | SPIROCYCLIC MDM2 MODULATOR AND USES THEREOF | NEWAVE PHARMACEUTICAL INC. (US) | 2022-07-28 | — | — | WO | disclosed |