Sugi Predict

Sugi Predict / Compounds / SCHEMBL29754385

SCHEMBL29754385

SCHEMBL29754385

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCSC)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)O)[C@@H](C)CC

nearest known ligand 0.76

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.64
▸ MAPK9 P45984 1/20 0.64
▸ MAPK10 P53779 1/20 0.64
▸ KEAP1 Q14145 1/20 0.61
▸ NPY2R P49146 7/20 0.60
▸ NPY4R P50391 7/20 0.60
▸ NPY5R Q15761 7/20 0.60
▸ NPY1R P25929 5/20 0.60
▸ EP300 Q09472 1/20 0.60
▸ HIF1A Q16665 1/20 0.60
▸ CALCR P30988 9/20 0.60
▸ RAMP3 O60896 6/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30028547 0.93 CALCR (0.65) KEAP1NPY2RNPY4RNPY5RNPY1R
SCHEMBL29649207 0.92 MAPK8 (0.58) MAPK8MAPK9MAPK10KEAP1NPY2R
SCHEMBL31182959 0.92 MAPK8 (0.67) MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL30495665 0.91 CALCR (0.65) KEAP1NPY2RNPY4RNPY5RNPY1R
SCHEMBL30438334 0.90 MAPK8 (0.61) MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL30883234 0.90 NPY2R (0.65) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL22263594 0.90 NPY2R (0.67) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30804648 0.90 NPY2R (0.63) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30712922 0.90 MAPK8 (0.67) MAPK8MAPK9MAPK10KEAP1NPY2R
SCHEMBL30938250 0.90 CALCR (0.67) MAPK8MAPK9MAPK10KEAP1NPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716516-B Phage display polypeptide VS specifically bound by chicken DEC-205 and application thereof 江苏省农业科学院 2023-06-13 — — CN disclosed
CN-114805494-B Chicken DEC-205 receptor affinity peptide DL and preparation method and application thereof 江苏省农业科学院 2023-06-13 — — CN disclosed
CN-114805494-A Chicken DEC-205 receptor affinity peptide DL and preparation method and application thereof 江苏省农业科学院 2022-07-29 — — CN disclosed
CN-114716516-A Chicken DEC-205 specific binding phage display polypeptide VS and application thereof 江苏省农业科学院 2022-07-08 — — CN disclosed