Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 9/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SI | P14410 | 3/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122716 | 1.00 | DYRK1A (0.46) | DYRK1AAAK1HASPINDYRK2ACHE | |
| SCHEMBL20123007 | 0.87 | DYRK1A (0.58) | DYRK1AHASPINDYRK2ACHEMAOA | |
| SCHEMBL30664315 | 0.87 | DYRK1A (0.58) | DYRK1AHASPINDYRK2ACHEMAOA | |
| SCHEMBL20123023 | 0.86 | DYRK1A (0.45) | DYRK1AAAK1HASPINDYRK2ACHE | |
| SCHEMBL29756351 | 0.86 | DYRK1A (0.45) | DYRK1AAAK1HASPINDYRK2ACHE | |
| SCHEMBL29756445 | 0.85 | DYRK1A (0.42) | DYRK1AAAK1HASPINACHEHTR2A | |
| SCHEMBL20122784 | 0.85 | DYRK1A (0.42) | DYRK1AAAK1HASPINACHEHTR2A | |
| Hydrochloric Acid SCHEMBL29756375 | 0.85 | DYRK1A (0.41) | DYRK1AAAK1HASPINACHEHTR2A | |
| SCHEMBL30664307 | 0.84 | DYRK1A (0.47) | DYRK1AAAK1HASPINDYRK2ACHE | |
| SCHEMBL20123000 | 0.84 | DYRK1A (0.47) | DYRK1AAAK1HASPINDYRK2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382496-B | Substituted pyrido [3,4-b ] indoles for the treatment of cartilage disorders | 赛诺菲 | 2022-08-09 | — | — | CN | disclosed |