SCHEMBL29760896

SCHEMBL29760896

CC(C)C[C@H](N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 3/20 0.52
▸ PTPN1 P18031 3/20 0.49
▸ BACE1 P56817 11/20 0.47
▸ ERAP2 Q6P179 1/20 0.46
▸ ERAP1 Q9NZ08 1/20 0.46
▸ LNPEP Q9UIQ6 1/20 0.46
▸ GNPAT O15228 1/20 0.45
▸ BACE2 Q9Y5Z0 1/20 0.43
▸ CTSD P07339 1/20 0.43
▸ EGFR P00533 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777802 0.97 FOLH1 (0.55) FOLH1PTPN1BACE1ERAP2ERAP1
SCHEMBL31042502 0.95 BACE1 (0.48) FOLH1PTPN1BACE1ERAP2ERAP1
SCHEMBL31750957 0.95 BACE1 (0.48) FOLH1PTPN1BACE1ERAP2ERAP1
SCHEMBL29760983 0.95 BACE1 (0.48) FOLH1PTPN1BACE1ERAP2ERAP1
SCHEMBL31672191 0.94 FOLH1 (0.50) FOLH1PTPN1BACE1BACE2CTSD
SCHEMBL31672189 0.94 FOLH1 (0.50) FOLH1PTPN1BACE1BACE2CTSD
SCHEMBL38658308 0.94 PTPN1 (0.51) FOLH1PTPN1BACE1BACE2CTSD
SCHEMBL38659780 0.94 PTPN1 (0.51) FOLH1PTPN1BACE1BACE2CTSD
SCHEMBL29777845 0.93 FOLH1 (0.56) FOLH1PTPN1BACE1ERAP2ERAP1
SCHEMBL30193392 0.92 FOLH1 (0.60) FOLH1ERAP2ERAP1LNPEPGNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide SHENZHEN TURIER BIOTECH CO., LTD. 2022-08-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide GCGR, GLP1R, GIPR FOLH1 405/4885PTPN1 2709/4885BACE1 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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