SCHEMBL29761900

SCHEMBL29761900

Cc1cc(NC(=O)c2ccc3c(c2)CCNC3)nn1Cc1cc(Cl)ccc1OCC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4091844 1.00 PTGER1 (1.00) PTGER1
Hydrochloric Acid SCHEMBL4104578 0.99 PTGER1 (1.00) PTGER1
SCHEMBL13693324 0.95 PTGER1 (0.98) PTGER1
Hydrochloric Acid SCHEMBL4096755 0.95 PTGER1 (1.00) PTGER1
SCHEMBL3056778 0.91 PTGER1 (0.84) PTGER1
Hydrochloric Acid SCHEMBL3056914 0.90 PTGER1 (0.84) PTGER1
SCHEMBL3578834 0.90 PTGER1 (0.81) PTGER1
SCHEMBL3058104 0.90 PTGER1 (0.81) PTGER1
Hydrochloric Acid SCHEMBL3049776 0.89 PTGER1 (0.82) PTGER1
Hydrochloric Acid SCHEMBL3583126 0.89 PTGER1 (0.82) PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289794-A1 COMPOUNDS AND METHODS FOR TREATING CANCER MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2025-09-18 US disclosed
US-12286413-B2 Compounds and methods for treating cancer MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-04-29 US disclosed
EP-4180041-A1 COMPOUNDS AND METHODS FOR TREATING CANCER Mayo Foundation for Medical Education and Research (US) 2023-05-17 EP disclosed
CN-113666853-B Biaryl compounds useful as ROR gamma modulators 上海辉启生物医药科技有限公司 2023-04-18 CN disclosed
US-20220411389-A1 COMPOUNDS AND METHODS FOR TREATING CANCER MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2022-12-29 US disclosed
EP-3808349-B1 COMPOUNDS AND METHODS FOR TREATING CANCER MAYO FOUND MEDICAL EDUCATION & RES (US) 2022-10-05 EP disclosed
US-11325892-B2 Compounds and methods for treating cancer MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2022-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11325892-B2 Compounds and methods for treating cancer SCD, CPT1B, CPT1A PTGER1 202/4885
US-20250289794-A1 COMPOUNDS AND METHODS FOR TREATING CANCER SCD, CPT1B, CPT1A PTGER1 202/4885
US-20220411389-A1 COMPOUNDS AND METHODS FOR TREATING CANCER SCD, CPT1B, CPT1A PTGER1 202/4885
US-12286413-B2 Compounds and methods for treating cancer SCD, CPT1B, CPT1A PTGER1 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.