SCHEMBL29762017

SCHEMBL29762017

CCOC(=O)c1cc(O)cc(-c2cc(O)cc(C(=O)OCC)c2)c1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.81
CA1 P00915 6/20 0.81
CA2 P00918 6/20 0.81
CA7 P43166 6/20 0.81
CA9 Q16790 6/20 0.81
CA14 Q9ULX7 6/20 0.81
ESR1 P03372 2/20 0.58
ESR2 Q92731 1/20 0.58
NR1H2 P55055 1/20 0.56
NR1H3 Q13133 1/20 0.56
CYP3A4 P08684 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B2 P37059 1/20 0.47
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
MAOA P21397 1/20 0.47
BCL2L1 Q07817 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20377203 1.00 CA12 (0.81) CA12CA1CA2CA7CA9
SCHEMBL39026 0.90 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL475700 0.90 CA12 (0.92) CA12CA1CA2CA7CA9
SCHEMBL2257945 0.85 CA12 (0.81) CA12CA1CA2CA7CA9
SCHEMBL2208614 0.83 CA12 (0.79) CA12CA1CA2CA7CA9
SCHEMBL57016 0.83 CA12 (0.79) CA12CA1CA2CA7CA9
SCHEMBL6264809 0.81 CA12 (0.76) CA12CA1CA2CA7CA9
SCHEMBL1664013 0.81 CA12 (0.75) CA12CA1CA2CA7CA9
SCHEMBL14374036 0.80 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL5415007 0.80 CA12 (0.73) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110191890-B Chemical substances for coating nanostructures 斯帕果纳米医学有限公司 2022-11-15 CN disclosed
US-11401376-B2 Chemical compounds for coating of nanostructures SPAGO NANOMEDICAL AB (SE) 2022-08-02 US disclosed