Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774089 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL48934 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL2396630 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL2631528 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL31348077 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ACDK8POLB | |
| SCHEMBL30751983 | 0.79 | POLB (0.62) | SMN1; SMN2MEN1KMT2ACDK8NTRK1 | |
| SCHEMBL6361845 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL11200266 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL7532390 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL3085802 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845776-A | Tetrahydrobenzo-quinoline sulfonamide derivatives useful as IGE modulators | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |