SCHEMBL29763585

SCHEMBL29763585

CC[C@@H](c1cccc(OCc2ccccc2)c1)[C@@H](C)C=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.53
MAOB P27338 5/20 0.52
MAOA P21397 1/20 0.52
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALOX5 P09917 1/20 0.50
CCNB2 O95067 1/20 0.48
CDK1 P06493 1/20 0.48
CDK4 P11802 1/20 0.48
CCNB1 P14635 1/20 0.48
CCND1 P24385 1/20 0.48
CCNB3 Q8WWL7 1/20 0.48
MEN1 O00255 1/20 0.47
SGMS2 Q8NHU3 1/20 0.46
NR4A2 P43354 1/20 0.46
MME P08473 1/20 0.44
ACE P12821 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18371748 1.00 BCHE (0.53) BCHEMAOBMAOAKMT2ASMN1; SMN2
SCHEMBL16871046 0.85 BCHE (0.53) BCHEMAOBMAOAKMT2ASMN1; SMN2
SCHEMBL16871064 0.85 BCHE (0.53) BCHEMAOBMAOAKMT2ASMN1; SMN2
SCHEMBL11831301 0.83 BCHE (0.58) BCHEMAOBMAOAKMT2ASMN1; SMN2
SCHEMBL19857059 0.83 KMT2A (0.56) BCHEMAOBKMT2ASMN1; SMN2ALOX5
SCHEMBL19857060 0.83 KMT2A (0.56) BCHEMAOBKMT2ASMN1; SMN2ALOX5
SCHEMBL16871513 0.82 KMT2A (0.51) BCHEMAOBKMT2ASMN1; SMN2ALOX5
SCHEMBL28057996 0.82 SMN1; SMN2 (0.51) BCHEMAOBKMT2ASMN1; SMN2ALOX5
SCHEMBL16871514 0.82 KMT2A (0.51) BCHEMAOBKMT2ASMN1; SMN2ALOX5
SCHEMBL16432400 0.81 MAOB (0.57) BCHEMAOBMAOAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3995492-A1 A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES SpecGx LLC (US) 2022-05-11 EP disclosed