SCHEMBL29763755

SCHEMBL29763755

CC(C)(C)c1cc(-c2cc(-c3ccccc3)ccc2OCCO)ccc1N1CCCC1

nearest known ligand 0.81

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARG P13631 13/20 0.81
RARA P10276 12/20 0.81
RARB P10826 12/20 0.81
SLC6A9 P48067 3/20 0.44
GBA1 P04062 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
AR P10275 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26199872 0.92 RARG (0.78) RARGRARARARBSLC6A9
Trifarotene SCHEMBL381493 0.90 RARG (1.00) RARGRARARARB
SCHEMBL382411 0.89 RARG (0.98) RARGRARARARB
SCHEMBL25040440 0.89 RARG (0.74) RARGRARARARBSLC6A9
SCHEMBL30244638 0.88 RARG (0.73) RARGRARARARBAR
SCHEMBL27337609 0.88 RARG (0.85) RARGRARARARB
SCHEMBL25040455 0.88 RARG (0.73) RARGRARARARBAR
SCHEMBL383438 0.87 RARG (0.78) RARGRARARARBSLC6A9
SCHEMBL25040467 0.87 RARG (0.84) RARGRARARARB
SCHEMBL382843 0.86 RARG (1.00) RARGRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4169512-A1 DERMATOLOGICAL COMPOSITION COMPRISING OLEOSOMES AND RETINOIDS, METHOD FOR PREPARING SAME AND USE THEREOF Galderma Research & Development (FR) 2023-04-26 EP claimed
EP-2874619-B1 O/W-EMULSION-TYPE TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING A RETINOID GALDERMA RES & DEV (FR) 2023-01-04 EP claimed
EP-2872116-B1 DERMATOLOGICAL COMPOSITION INCLUDING OLEOSOMES AND RETINOIDS, METHOD FOR PREPARING SAME AND USE THEREOF GALDERMA RES & DEV (FR) 2022-10-26 EP claimed
EP-2854802-B2 TOPICAL OIL IN WATER EMULSION COMPOSITIONS COMPRISING A RETINOID GALDERMA RES & DEV (FR) 2022-08-24 EP claimed
EP-2854803-B2 TOPICAL GEL COMPOSITION COMPRISING A SOLUBILIZED SPECIFIC RETINOID GALDERMA RES & DEV (FR) 2022-08-24 EP claimed
EP-4169512-A1 DERMATOLOGICAL COMPOSITION COMPRISING OLEOSOMES AND RETINOIDS, METHOD FOR PREPARING SAME AND USE THEREOF Galderma Research & Development (FR) 2023-04-26 EP disclosed
EP-4169512-A1 DERMATOLOGICAL COMPOSITION COMPRISING OLEOSOMES AND RETINOIDS, METHOD FOR PREPARING SAME AND USE THEREOF Galderma Research & Development (FR) 2023-04-26 EP disclosed
EP-2874619-B1 O/W-EMULSION-TYPE TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING A RETINOID GALDERMA RES & DEV (FR) 2023-01-04 EP disclosed
EP-2872116-B1 DERMATOLOGICAL COMPOSITION INCLUDING OLEOSOMES AND RETINOIDS, METHOD FOR PREPARING SAME AND USE THEREOF GALDERMA RES & DEV (FR) 2022-10-26 EP disclosed
EP-2854802-B2 TOPICAL OIL IN WATER EMULSION COMPOSITIONS COMPRISING A RETINOID GALDERMA RES & DEV (FR) 2022-08-24 EP disclosed
EP-2854803-B2 TOPICAL GEL COMPOSITION COMPRISING A SOLUBILIZED SPECIFIC RETINOID GALDERMA RES & DEV (FR) 2022-08-24 EP disclosed