Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.77 |
| ▸ | IDH2 | P48735 | 16/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799043 | 1.00 | IDH1 (0.77) | IDH1IDH2 | |
| SCHEMBL21799085 | 1.00 | IDH1 (0.77) | IDH1IDH2 | |
| SCHEMBL20289919 | 1.00 | IDH1 (0.77) | IDH1IDH2 | |
| SCHEMBL20289879 | 1.00 | IDH1 (0.77) | IDH1IDH2 | |
| SCHEMBL30341805 | 1.00 | IDH1 (0.77) | IDH1IDH2 | |
| SCHEMBL24170400 | 0.97 | IDH1 (0.72) | IDH1IDH2 | |
| SCHEMBL23625845 | 0.92 | IDH1 (0.66) | IDH1IDH2 | |
| SCHEMBL21799147 | 0.92 | IDH1 (0.75) | IDH1IDH2 | |
| SCHEMBL21799145 | 0.92 | IDH1 (0.75) | IDH1IDH2 | |
| SCHEMBL20289610 | 0.92 | IDH1 (0.75) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109075-B | Mutant IDH1 and IDH2 inhibitors | 伊莱利利公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115109075-A | Mutant IDH1 and IDH2 inhibitors | 伊莱利利公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-110072867-B | 7-phenylethylamino-4H-pyrimido [4,5-D ] [1,3] oxazin-2-one compounds as inhibitors of mutant IDH1 and IDH2 | 伊莱利利公司 | 2022-07-08 | — | — | CN | disclosed |