Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079651 | 0.88 | CRBN (0.43) | CRBNDDB1IKZF3IKZF2TNF | |
| SCHEMBL29768075 | 0.81 | CRBN (0.36) | CRBNDDB1IKZF3IKZF2 | |
| SCHEMBL31342076 | 0.79 | CRBN (0.46) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL29079659 | 0.78 | CRBN (0.40) | CRBNDDB1IKZF3TNFIL1B | |
| Hydrochloric Acid SCHEMBL29079560 | 0.77 | CRBN (0.39) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL29768218 | 0.77 | CRBN (0.42) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL21071320 | 0.77 | DDB1 (0.54) | CRBNDDB1IKZF3IKZF2 | |
| SCHEMBL30574628 | 0.76 | CRBN (0.41) | CRBNDDB1IKZF3TNFIL1B | |
| Hydrochloric Acid SCHEMBL30392700 | 0.76 | DDB1 (0.53) | CRBNDDB1IKZF3IKZF2 | |
| SCHEMBL29079566 | 0.76 | CRBN (0.50) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161414-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND APPLICATION THEREOF | 成都茵创园医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |