Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CCNH | P51946 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769756 | 1.00 | EGFR (0.53) | EGFRCCNE1CDK2CCNT1CCNT2 | |
| SCHEMBL5307919 | 1.00 | EGFR (0.53) | EGFRCCNE1CDK2CCNT1CCNT2 | |
| SCHEMBL23041102 | 1.00 | EGFR (0.53) | EGFRCCNE1CDK2CCNT1CCNT2 | |
| Hydrochloric Acid SCHEMBL23041121 | 0.98 | EGFR (0.51) | EGFRCCNE1CDK2CCNT1CCNT2 | |
| Hydrochloric Acid SCHEMBL23041118 | 0.98 | EGFR (0.51) | EGFRCCNE1CDK2CCNT1CCNT2 | |
| Trifluoroacetic Acid SCHEMBL23041104 | 0.87 | EGFR (0.42) | EGFRCCNE1CDK2CCNT1CCNT2 | |
| SCHEMBL27280767 | 0.87 | MAPT (0.51) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5304083 | 0.86 | MEN1 (0.57) | CCNE1CDK2CCNT1CCNE2CDK9 | |
| SCHEMBL29769753 | 0.86 | MEN1 (0.57) | CCNE1CDK2CCNT1CCNE2CDK9 | |
| SCHEMBL5304078 | 0.86 | MEN1 (0.57) | CCNE1CDK2CCNT1CCNE2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114727997-A | Compounds for the treatment of pain | 卡希夫生物科学有限公司 | 2022-07-08 | — | — | CN | disclosed |