Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326606 | 1.00 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL29773940 | 0.84 | — | — | |
| SCHEMBL21326702 | 0.80 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL30090025 | 0.80 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL21326686 | 0.74 | IRAK4 (0.32) | IRAK4 | |
| SCHEMBL21326688 | 0.74 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL24408824 | 0.72 | GRM5 (0.30) | — | |
| SCHEMBL24408934 | 0.71 | — | — | |
| SCHEMBL29634708 | 0.71 | — | — | |
| SCHEMBL21326685 | 0.71 | BRD4 (0.36) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890829-B | Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2022-07-15 | — | — | CN | disclosed |