Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23167500 | 1.00 | HDAC6 (0.53) | HDAC6HDAC1MEN1KMT2ATNF | |
| SCHEMBL30324527 | 0.83 | HDAC1 (0.51) | HDAC6HDAC1MEN1KMT2ATNF | |
| SCHEMBL23202436 | 0.79 | HDAC6 (0.77) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL25138289 | 0.76 | HDAC6 (0.47) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL29228583 | 0.75 | HDAC1 (0.87) | HDAC6HDAC1MEN1KMT2ATNF | |
| SCHEMBL30960755 | 0.75 | HDAC1 (0.87) | HDAC6HDAC1MEN1KMT2ATNF | |
| SCHEMBL23202576 | 0.74 | HDAC6 (0.43) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL720087 | 0.74 | HDAC6 (0.55) | HDAC6HDAC1MEN1KMT2ARAB9A | |
| SCHEMBL26050914 | 0.73 | HDAC1 (0.56) | HDAC6HDAC1HDAC3HDAC8SMN1; SMN2 | |
| SCHEMBL23202608 | 0.73 | HDAC6 (0.66) | HDAC6HDAC1HDAC3HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037670-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | Tenaya Therapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |