Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29779604 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| SCHEMBL14862575 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| SCHEMBL2085504 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| SCHEMBL14862093 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| Hydrochloric Acid SCHEMBL16292918 | 0.98 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| Hydrochloric Acid SCHEMBL4799050 | 0.98 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| SCHEMBL20217280 | 0.92 | KCNA5 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| SCHEMBL12789439 | 0.92 | KCNA5 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| SCHEMBL14862495 | 0.92 | KCNA5 (0.44) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 | |
| Hydrochloric Acid SCHEMBL15400032 | 0.91 | KCNA5 (0.43) | SLC6A4SLC6A2SLC6A3KCNA5KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037670-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | Tenaya Therapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |