Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127125 | 0.87 | EGFR (0.52) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL29781303 | 0.85 | EGFR (0.57) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30126178 | 0.84 | EGFR (0.58) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30125906 | 0.83 | EGFR (0.56) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30126644 | 0.83 | EGFR (0.56) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30127567 | 0.83 | EGFR (0.56) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30127293 | 0.83 | EGFR (0.56) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30125843 | 0.82 | EGFR (0.54) | EGFRERBB2SRCDRD2KDR | |
| SCHEMBL30126650 | 0.82 | EGFR (0.52) | EGFR | |
| SCHEMBL29781273 | 0.81 | PIK3CD (0.48) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170052-A1 | QUINAZOLINE DERIVATIVES, PYRIDOPYRIMIDINE DERIVATIVES, PYRIMIDOPYRIMIDINE DERIVATIVES, AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |