Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 4/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745555 | 1.00 | PDE4B (0.44) | PDE4BHPGDSTSUSP30RECQL | |
| SCHEMBL23230962 | 1.00 | PDE4B (0.44) | PDE4BHPGDSTSUSP30RECQL | |
| SCHEMBL23216739 | 0.90 | EED (0.48) | PDE4BSTSEEDRBBP4SUZ12 | |
| SCHEMBL23214820 | 0.88 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL29782176 | 0.85 | HPGD (0.47) | HPGDSTSUSP30RECQLEED | |
| SCHEMBL29782200 | 0.85 | HPGD (0.47) | HPGDSTSUSP30RECQLEED | |
| SCHEMBL29745534 | 0.85 | HPGD (0.47) | HPGDSTSUSP30RECQLEED | |
| SCHEMBL29745326 | 0.85 | HPGD (0.47) | HPGDSTSUSP30RECQLEED | |
| SCHEMBL29745669 | 0.85 | HPGD (0.47) | HPGDSTSUSP30RECQLEED | |
| SCHEMBL29782185 | 0.85 | HPGD (0.47) | HPGDSTSUSP30RECQLEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114727991-A | Arylmethylene heterocyclic compounds as Kv1.3 potassium SHAKER channel blockers | D·E·萧尔研究有限责任公司 | 2022-07-08 | — | — | CN | disclosed |