Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
| ▸ | TEC | P42680 | 2/20 | 1.00 |
| ▸ | TXK | P42681 | 2/20 | 1.00 |
| ▸ | BMX | P51813 | 2/20 | 1.00 |
| ▸ | JAK3 | P52333 | 2/20 | 1.00 |
| ▸ | ITK | Q08881 | 2/20 | 1.00 |
| ▸ | ERBB4 | Q15303 | 2/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17699673 | 1.00 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL28165085 | 0.90 | BTK (0.81) | BTKTECTXKBMXJAK3 | |
| SCHEMBL29782622 | 0.89 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL17699831 | 0.89 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL29782585 | 0.89 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL17699624 | 0.89 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL17699625 | 0.89 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL17699971 | 0.86 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL29782533 | 0.86 | BTK (1.00) | BTKTECTXKBMXJAK3 | |
| SCHEMBL29782644 | 0.85 | BTK (1.00) | BTKTECTXKBMXJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |