SCHEMBL29782614

SCHEMBL29782614

Cc1ccc2c(c1)C(=O)N(c1cccc(-c3ccc(C(N)=O)c4[nH]c(C)c(C)c34)c1C)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BTK Q06187 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17699531 1.00 BTK (1.00) BTK
SCHEMBL17699979 0.91 BTK (1.00) BTK
SCHEMBL29782508 0.91 BTK (1.00) BTK
SCHEMBL149011 0.86 BTK (0.75) BTK
SCHEMBL148232 0.83 BTK (0.70) BTK
SCHEMBL151321 0.82 BTK (0.69) BTK
SCHEMBL123386 0.82 BTK (0.69) BTK
SCHEMBL148788 0.81 BTK (0.68) BTK
SCHEMBL148370 0.81 BTK (0.67) BTK
SCHEMBL123162 0.81 BTK (0.67) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511209-B Indole carboxamide compounds useful as kinase inhibitors 百时美施贵宝公司 2022-07-05 CN disclosed