Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17699720 | 1.00 | BTK (0.62) | BTKCHEK1KCNH2FLT3 | |
| SCHEMBL17699634 | 0.93 | BTK (0.63) | BTKCHEK1KCNH2 | |
| SCHEMBL17699859 | 0.93 | BTK (0.63) | BTKCHEK1KCNH2 | |
| SCHEMBL29782460 | 0.93 | BTK (0.63) | BTKCHEK1KCNH2 | |
| SCHEMBL29782781 | 0.93 | BTK (0.63) | BTKCHEK1KCNH2 | |
| SCHEMBL17699570 | 0.93 | BTK (0.63) | BTKCHEK1KCNH2 | |
| SCHEMBL29782505 | 0.86 | BTK (0.69) | BTK | |
| SCHEMBL17699525 | 0.86 | BTK (0.69) | BTK | |
| SCHEMBL23231101 | 0.80 | BTK (0.43) | BTKCHEK1KCNH2 | |
| SCHEMBL17699641 | 0.79 | BTK (0.61) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |