SCHEMBL29783279

SCHEMBL29783279

CCCCC(C(=O)O)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.68
ALDH1A1 P00352 3/20 0.68
MAPK1 P28482 2/20 0.68
KDM4E B2RXH2 1/20 0.68
TP53 P04637 1/20 0.68
GLA P06280 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2D6 P10635 1/20 0.68
HPGD P15428 1/20 0.68
ALOX12 P18054 1/20 0.68
NFKB1 P19838 1/20 0.68
APEX1 P27695 1/20 0.68
HSD17B10 Q99714 1/20 0.68
GAA P10253 2/20 0.60
KMT2A Q03164 2/20 0.51
HIF1A Q16665 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
DNMT1 P26358 7/20 0.49
CYP2C19 P33261 1/20 0.48
DNMT3B Q9UBC3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133528 1.00 POLB (0.68) POLBALDH1A1MAPK1KDM4ETP53
Hydrochloric Acid SCHEMBL8187825 0.98 POLB (0.66) POLBALDH1A1MAPK1KDM4ETP53
Hydrochloric Acid SCHEMBL7757351 0.98 POLB (0.66) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL28775935 0.95 POLB (0.66) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL31661829 0.94 POLB (0.64) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL5989512 0.94 POLB (0.64) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL9899331 0.94 POLB (0.64) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL28775906 0.94 POLB (0.64) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL30165546 0.90 POLB (0.71) POLBALDH1A1MAPK1KDM4ETP53
SCHEMBL2888134 0.90 POLB (0.71) POLBALDH1A1MAPK1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288481-B1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS UNIV BERLIN TECH (DE) 2026-05-06 EP disclosed
US-20240301140-A1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS Technische Universität Berlin (DE) 2024-09-12 US disclosed
EP-4288481-A1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS Technische Universität Berlin (DE) 2023-12-13 EP disclosed
EP-4164690-A1 SMALL MOLECULE VE-PTP INHIBITORS Ripka, Amy (US) 2023-04-19 EP disclosed
WO-2022167637-A1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS Technische Universität Berlin (DE) 2022-08-11 WO disclosed
EP-4039730-A1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS Technische Universität Berlin (DE) 2022-08-10 EP disclosed